Even though flowers may seem small, the petals they possess collectively offer a significant amount of surface area. This concept extends to the microscopic realm, where nanoflowers, compound combinations in chemistry that resemble plantlike shapes, exist. A research team from the University of Genoa in Italy has developed a new nanostructure featuring carnation-like nanoflowers with ample surface area to accommodate multiple wound-healing drug molecules.
The innovative medical solution is outlined in a study published in the journal ACS Applied Bio Materials. The bandage prototype utilizes two polyphenol-based materials, namely copper phosphate and tannic acid, known for their anti-inflammatory and antibiotic properties. When combined and placed in a saline solution, these materials self-assemble into flower-like structures. Subsequently, these nanoflowers are carefully attached to small strips of electrospun nanofabric.
The research team stated in their study, “Polyphenols, natural compounds rich in phenolic structures, have garnered attention for their beneficial properties in biomedical applications such as antioxidant, anti-inflammatory, antibacterial, and anticancer effects. The eco-friendly synthesis of polyphenol-based materials holds significant importance.”
After preparing the dressings, the team introduced the nanoflower bandage samples to cultures of harmful bacteria, including E. coli, Pseudomonas aeruginosa, and Staphylococcus aureus. An announcement on January 31st revealed that the nanoflower-coated fabrics not only deactivated the bacteria but also disrupted antibiotic-resistant biofilms while safeguarding lab-grown human cells.
Researchers believe that their novel approach using nanoflowers is cost-effective and highly effective, offering improved wound healing acceleration and infection combat capabilities. The potential applications of nanoflowers extend beyond medicine. A study published in Advanced Materials in October 2024 suggested uses in real-time imaging, wastewater purification, and microrobotics.
